Research
Division Chief and Professor Jack Sobel focuses his research on HIV/AIDS.
Active Grants:
- NIH – CPCRA Clinical Trials Unit to George Washington University in support of AIDS.
- Ryan White Care HIV/AIDS Treatment Modernization Act – Detroit Department of Health and Wellness Promotion.
- HRSA – Outpatient Early Intervention Services (EIS) with Respect to HIV Disease.
- Johnson & Johnson. Focused giving grant. PCR-based analysis of dynamic changes in vaginal bacteriophage and bacterial species in women with recurrent bacterial vaginosis.
- Merck – A randomized double blind placebo controlled trial of caspofungin vs. placebo as prophylaxis of invasive candidiasis in high risk adults in the critical care.
- Abbott Research Group – A clinical study of treatment of symptomatic bacterial vaginosis with water works douching device versus non-treatment.
- Presutti Laboratories – A phase 3 randomized, multi-center, double-blind, double-dummy, placebo-controlled treatment trial of bacterial vaginosis with tinidazole oral tablets.
Recent Awards:
- Pfizer Research Award. An analysis of voriconazole resistance mechanisms using a high copy plasmid transformation system in Candida albicans.
- Best Doctors 2008 award for southeastern Michigan.
Facilities:
The Wayne State University laboratory is located in the Lande Building with 1200 square feet of bench space and an additional 200 square feet in an adjacent 350 with a walk-in cold room.
Separate sections of 356 are used for radioisotope and for media preparation.
- Freezers (2-20C, 2 – 70C)
- Refrigerators (3)
- Laminar flow hood
- UV hood
- 2 Robotic thermocyclers
- 1 Real time thermocycler
- Multifunctional microplate reader
- Floor centrifuge
- 3 Microfuges
- 2 large water baths
- Multiple individual water baths
- 5 incubators
- Electroporator
- Numerous agarose gel electrophoresis chambers and power supplies
- Digital camera and ultraviolet transilluminator
- Phase contrast microscope, scanner, pipettors