Division Chief and Professor Jack Sobel focuses his research on HIV/AIDS.

Active Grants:

• NIH – CPCRA Clinical Trials Unit to George Washington University in support of AIDS.
• Ryan White Care HIV/AIDS Treatment Modernization Act – Detroit Department of Health and Wellness Promotion.
• HRSA – Outpatient Early Intervention Services (EIS) with Respect to HIV Disease.
• Johnson & Johnson. Focused giving grant. PCR-based analysis of dynamic changes in vaginal bacteriophage and bacterial species in women with recurrent bacterial vaginosis.
• Merck – A randomized double blind placebo controlled trial of caspofungin vs. placebo as prophylaxis of invasive candidiasis in high risk adults in the critical care.
• Abbott Research Group – A clinical study of treatment of symptomatic bacterial vaginosis with water works douching device versus non-treatment.
• Presutti Laboratories – A phase 3 randomized, multi-center, double-blind, double-dummy, placebo-controlled treatment trial of bacterial vaginosis with tinidazole oral tablets.

Recent Awards:

• Pfizer Research Award. An analysis of voriconazole resistance mechanisms using a high copy plasmid transformation system in Candida albicans.
• Best Doctors 2008 award for southeastern Michigan.

Facilities:
The Wayne State University laboratory is located in the Lande Building with 1200 square feet of bench space and an additional 200 square feet in an adjacent 350 with a walk-in cold room.

Separate sections of 356 are used for radioisotope and for media preparation.

• Freezers (2-20C, 2 – 70C)
• Refrigerators (3)
• Laminar flow hood
• UV hood
• 2 Robotic thermocyclers
• 1 Real time thermocycler
• Multifunctional microplate reader
• Floor centrifuge
• 3 Microfuges
• 2 large water baths
• Multiple individual water baths
• 5 incubators
• Electroporator
• Numerous agarose gel electrophoresis chambers and power supplies
• Digital camera and ultraviolet transilluminator
• Phase contrast microscope, scanner, pipettors